People have created bionic robots, biological hybrid robots and the emergence of Xenobots is seen as creating new creatures. Although programming matters also have similar characteristics and advantages of living things, they are more accepted in bioethics. As a prototype design based on the theory of 4D printing technology and bionics, biological products are used to envision the next era when information is more closely integrated with the material world. Through this consideration, people can think about how the definition of biological is being changed by programming matter and envision whether future products can be biological in a new design and manufacturing generation.